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Article

Transition from squamous cell carcinoma to adenocarcinoma in adenosquamous carcinoma of the lung.

The American journal of pathology - 1 Apr 2000

Kanazawa H, Ebina M, Ino-Oka N, Shimizukawa M, Takahashi T, Fujimura S, Imai T, Nukiwa T

Abstract excerpt

The heterogeneity of tumor cells is frequently observed in lung cancer, but the clonality of these cells has not yet been established. The distinct components of 12 lung adenosquamous carcinomas were compared by genetic alterations of p53 and K-ras, chromosomal abnormalities at 9p21 and 9q31-32, and immunohistochemical reactions. The immunoreactivity of p53 was consistent in both adenocarcinomatous and squamous...

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Share to Adenocarcinoma
Share to Carcinoma, Adenosquamous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Chromosomes, Human, Pair 9

Share to Genes, ras

Share to Immunohistochemistry

Share to Lung Neoplasms

Share to Tumor Suppressor Protein p53

Source

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Identifiers

PMID: 10751354
DOI: 10.1016/S0002-9440(10)64999-1
PMCID: PMC1876884

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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