Article
EGFR mutation exists in squamous cell lung carcinoma.
Pathology - 1 Apr 2020
Cheung Alvin Ho-Kwan, Tong Joanna Hung-Man, Chung Lau-Ying, Chau Shuk-Ling, Ng Calvin Sze-Hang, Wan Innes Y P, To Ka-Fai
Abstract excerpt
Whether EGFR mutation occurs in lung squamous cell carcinoma (SCC) remains a controversial issue. Although numerous trials have shown positive response to tyrosine kinase inhibitors in SCC, these observations have not been well correlated with presence or absence of EGFR mutation. A complicating issue is that adenosquamous carcinoma, a mimic of SCC, frequently harbours EGFR mutations. We evaluated the EGFR...
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