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Article

Independent regulation of the myotonic dystrophy 1 locus genes postnatally and during adult skeletal muscle regeneration.

The Journal of biological chemistry - 30 Jun 2000

Eriksson M, Ansved T, Edstrom L, Wells D J, Watt D J, Anvret M, Carey N

Abstract excerpt

Myotonic dystrophy is caused by a CTG(n) expansion in the 3'-untranslated region of a serine/threonine protein kinase gene (DMPK), which is flanked by two other genes, DMWD and SIX5. One hypothesis to explain the wide-ranging effects of this expansion is that, as the mutation expands, it alters the expression of one or more of these genes. The effects may vary in different tissues and developmental stages, but it...

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Source

Identifiers

PMID: 10748037
DOI: 10.1074/jbc.M001592200

Genes

DMPK
SIX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Independent regulation of the myotonic dystrophy 1 locus genes postnatally and during adult skeletal muscle regeneration.PMID 10748037Read ↗

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