Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100.

Thrombosis and haemostasis - 1 Feb 2000

Homoncik M, Jilma B, Hergovich N, Stohlawetz P, Panzer S, Speiser W

Abstract excerpt

BACKGROUND: Anti-platelet drug therapy is currently performed without monitoring, because the established method of platelet aggregometry is cumbersome. The recently developed platelet function analyzer PFA-100 measures shear stress dependent, collagen epinephrine (CEPI) and collagen adenosine diphosphate (CADP) induced platelet plug formation. As the PFA-100 provides a valuable tool to detect patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Diphosphate
Share to Aspirin
Share to Blood Coagulation Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epinephrine

Share to Fibrinolytic Agents

Share to Integrin alpha2

Share to Platelet Aggregation

Share to Platelet Count

Source

Identifiers

PMID: 10739392

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Monitoring of aspirin (ASA) pharmacodynamics with the platelet function analyzer PFA-100.PMID 10739392Read ↗

Platelet responsiveness to in vitro aspirin is independent of COX-1 and COX-2 protein levels and polymorphisms.Semantic proximity Read ↗

Variability in platelet responses to collagen--comparison between whole blood perfusions, traditional platelet function tests and PFA-100.Semantic proximity Read ↗

Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients.Semantic proximity Read ↗

Antithrombotic and Prohemorrhagic Actions of Different Concentrations of Apixaban in Patients Exposed to Single and Dual Antiplatelet RegimensSemantic proximity Read ↗

Recent developments in the use of antiplatelet agents to prevent cardiovascular events.Semantic proximity Read ↗

The GPIIIa PlA polymorphism and the platelet hyperactivity in Tunisian patients with stable coronary artery disease treated with aspirin.Semantic proximity Read ↗

Assessment of platelet-derived thrombogenicity with the total thrombus-formation analysis system in coronary artery disease patients receiving antiplatelet therapy.Semantic proximity Read ↗

A randomized clinical trial comparing point-of-care platelet function assays and bleeding time in healthy subjects treated with aspirin or clopidogrel.Semantic proximity Read ↗

Effects of Antiplatelet Drugs on Platelet-Dependent Coagulation ReactionsSemantic proximity Read ↗

Interdonor variability of platelet response to thrombin receptor activation: influence of PlA2 polymorphism.Semantic proximity Read ↗

A practical technique for clinicians to approximate platelet function after fifteen-minutes using thromboelastographySemantic proximity Read ↗

Prediction of the excessive perioperative bleeding in patients undergoing coronary artery bypass grafting: role of aspirin and platelet glycoprotein IIIa polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.