Article
A randomized clinical trial comparing point-of-care platelet function assays and bleeding time in healthy subjects treated with aspirin or clopidogrel.
Platelets - 1 Jan 2012
Chen Fabian, Maridakis Victor, O'neill Edward A, Beals Chan, Radziszewski Waldemar, de Lepeleire Inge, Van Dyck Kristien, Depré Marleen, Bolognese James A, de Hoon Jan, Jacquemin Marc
Abstract excerpt
Traditional assays of the coagulation status of patients, bleeding time assessment (BT) and light transmission aggregometry (LTA), are useful in clinical drug development. However, these assays are both labor intensive and expensive. BT results can be operator dependent and by its nature can inhibit subject enrollment in a clinical trial. The preparation of platelet-rich plasma necessary for LTA requires...
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