Article
Ovarian differentiation and gonadal failure.
American journal of medical genetics - 29 Dec 1999
Simpson J L, Rajkovic A
Abstract excerpt
Ovarian failure can result from several different genetic mechanisms-X chromosomal abnormalities, autosomal recessive genes causing various types of XX gonadal dysgenesis, and autosomal dominant genes. The number and precise location of loci on the X are still under investigation, but it is clear that, in aggregate, these genes are responsible for ovarian maintenance, given that monosomy X shows germ cells that...
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