Article
Genetic and phenotypic heterogeneity in ovarian failure: overview of selected candidate genes.
Annals of the New York Academy of Sciences - 1 Jan 2008
Simpson Joe Leigh
Abstract excerpt
Ovarian failure is heterogeneous, both in cause and in phenotype. Women whose menses cease prior to age 40 years and have menopausal FSH levels are traditionally considered by clinicians to have the diagnosis of "premature ovarian failure" (POF). In fact, however, the ovarian function in this disorder is in reality a continuum of impairment in ovarian responsiveness. For this reason the term "primary ovarian...
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