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An update on primary ovarian insufficiency

1 Aug 2012

Abstract excerpt

Primary ovarian insufficiency (POI) occurs in about 1% of female population under the age of 40, leading to reproductive problems, an earlier encounter with menopausal symptoms, and complicated diseases. There are three presumable mechanisms involved in the development of POI, namely apoptosis acceleration, follicular maturation blocking and premature follicle activation, through the following studied causes: (i)...

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PMID: 22932883
DOI: 10.1007/s11427-012-4355-2

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