Article
Secreted enzymatic activities of wild-type and pilD-deficient Legionella pneumophila.
Infection and immunity - 1 Apr 2000
Aragon V, Kurtz S, Flieger A, Neumeister B, Cianciotto N P
Abstract excerpt
Legionella pneumophila, the agent of Legionnaires' disease, is an intracellular pathogen of protozoa and macrophages. Previously, we had determined that the Legionella pilD gene is involved in type IV pilus biogenesis, type II protein secretion, intracellular infection, and virulence. Since the loss of pili and a protease do not account for the infection defect exhibited by a pilD-deficient strain, we sought to...
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