Article
Effects of orbital spaceflight on human osteoblastic cell physiology and gene expression.
Bone - 1 Apr 2000
Harris S A, Zhang M, Kidder L S, Evans G L, Spelsberg T C, Turner R T
Abstract excerpt
During long-term spaceflight, astronauts lose bone, in part due to a reduction in bone formation. It is not clear, however, whether the force imparted by gravity has direct effects on bone cells. To examine the response of bone forming cells to weightlessness, human fetal osteoblastic (hFOB) cells were cultured during the 17 day STS-80 space shuttle mission. Fractions of conditioned media were collected during...
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