Article
Aging affects the association between endothelial nitric oxide synthase gene polymorphism and acute myocardial infarction in the Korean male population.
The Korean journal of internal medicine - 1 Jan 2000
Park J E, Lee W H, Hwang T H, Chu J A, Kim S, Choi Y H, Kim J S, Kim D K, Lee S H, Hong K P, Seo J D, Lee W R
Abstract excerpt
OBJECTIVES: The aging process affects responsiveness and other functions of endothelium and vascular smooth muscle cells, predisposing the old vessels to the development of atherosclerotic lesions. Endothelial nitric oxide synthase (ecNOS) gene polymorphisms were shown to affect the occurrence of acute myocardial infarction (AMI). We hypothesized that aging may affect the association between the ecNOS gene...
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