Article
Genetic analysis of SecA-SecY interaction required for spore development in Bacillus subtilis.
FEMS microbiology letters - 15 Mar 2000
Kobayashi H, Ohashi Y, Nanamiya H, Asai K, Kawamura F
Abstract excerpt
All spontaneous suppressor mutations obtained from a secA12 sporulation-defective mutant in Bacillus subtilis were localized in highly conserved membrane-spanning regions of SecY. The expression of early sporulation genes, kinA and spo0A encoding a histidine kinase and a transcription regulator for several sporulation genes, respectively, was restored in these suppressor mutants. These results indicate that the...
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