Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genotypic associations of the hepatic secretion of VLDL apolipoprotein B-100 in obesity.

Journal of lipid research - 1 Mar 2000

Watts G F, Riches F M, Humphries S E, Talmud P J, van Bockxmeer F M

Abstract excerpt

We examined the effect of genetic polymorphisms of proteins regulating intrahepatic processing of apolipoprotein B-100 (apoB) and the supply of neutral lipids to the liver on the hepatic secretion of very low density lipoprotein (VLDL) apoB in obesity. Hepatic secretion of very low density apolipoprotein B-100 (VLDL apoB) was measured using an infusion of [1-(13)C]leucine in 29 obese men. Isotopic enrichment and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Apolipoprotein B-100
Share to Apolipoproteins B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CETP gene

Share to Genotype

Share to Lipoproteins, VLDL

Share to Obesity

Source

Identifiers

PMID: 10706596

Genes

CETP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genotypic associations of the hepatic secretion of VLDL apolipoprotein B-100 in obesity.PMID 10706596Read ↗

Apolipoprotein B signal peptide and apolipoprotein E genotypes as determinants of the hepatic secretion of VLDL apoB in obese men.Semantic proximity Read ↗

Genetic determinants of apolipoprotein B-100 kinetics.Semantic proximity Read ↗

ATP-binding cassette transporter G8 gene as a determinant of apolipoprotein B-100 kinetics in overweight men.Semantic proximity Read ↗

Kinetics of very-low-density lipoprotein apolipoprotein B-100 in normolipidemic subjects: pooled analysis of stable-isotope studies.Semantic proximity Read ↗

Microsomal triglyceride transfer protein -493T variant reduces IDL plus LDL apoB production and the plasma concentration of large LDL particles.Semantic proximity Read ↗

Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro.Semantic proximity Read ↗

Variation in Niemann-Pick C1-like 1 gene as a determinant of apolipoprotein B-100 kinetics and response to statin therapy in centrally obese men.Semantic proximity Read ↗

Effects of TM6SF2 E167K on hepatic lipid and very low-density lipoprotein metabolism in humans.Semantic proximity Read ↗

Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations.Semantic proximity Read ↗

A common apolipoprotein B signal peptide polymorphism modifies the relation between plasma non-esterified fatty acids and triglyceride concentration in men.Semantic proximity Read ↗

Missense mutation Q384K in the APOB gene affecting the large lipid transfer module of apoB reduces the secretion of apoB-100 in the liver without reducing the secretion of apoB-48 in the intestine.Semantic proximity Read ↗

Hepatic apolipoprotein E expression promotes very low density lipoprotein-apolipoprotein B production in vivo in miceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.