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Article

Candidate genes for the hypoxic tumor phenotype.

Cancer research - 15 Feb 2000

Koong A C, Denko N C, Hudson K M, Schindler C, Swiersz L, Koch C, Evans S, Ibrahim H, Le Q T, Terris D J, Giaccia A J

Abstract excerpt

In this study, we have analyzed changes induced by hypoxia at the transcriptional level of genes that could be responsible for a more aggressive phenotype. Using a series of DNA array membranes, we identified a group of hypoxia-induced genes that included plasminogen activator inhibitor-1 (PAI-1), insulin-like growth factor-binding protein 3 (IGFBP-3), endothelin-2, low-density lipoprotein receptor-related...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10706099

Genes

BCL2
BIK
MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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