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Article

Modeling the evolution of genetic architecture: A continuum of alleles model with pairwise AxA epistasis.

Journal of theoretical biology - 21 Mar 2000

Wagner G P, Mezey J

Abstract excerpt

A continuum of alleles model with pair-wise AxA epistasis is proposed and its transmission genetic, and variational properties are analysed. The basic idea is that genes control the values of underlying variables, which affect the genotypic value of phenotypic characters proportional to a "scaling factor". Epistasis is the influence of one gene on the average effect of another gene. In this model, epistasis is...

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PMID: 10704300
DOI: 10.1006/jtbi.2000.1074

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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