Titanium dioxide ceramics control the differentiated phenotype of cardiac muscle cells in culture.

doi:10.1016/s0142-9612(99)00189-1

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Article

Titanium dioxide ceramics control the differentiated phenotype of cardiac muscle cells in culture.

Biomaterials - 1 Mar 2000

Polonchuk L, Elbel J, Eckert L, Blum J, Wintermantel E, Eppenberger H M

Abstract excerpt

A new approach, the cultivation of heart muscle cells on biocompatible scaffolds made from titanium dioxide ceramics was established to provide a mechanism for in vitro engineering of a vital heart tissue. Terminally differentiated ventricular myocytes isolated from hearts of adult rats were kept in primary culture for long periods of time and used as an experimental model. The microenvironmental properties of...

Topics

Animals
Biocompatible Materials
Cell Adhesion
Cell Culture Techniques
Cell Differentiation
Cells, Cultured
Ceramics
Female
Gels
Heart
Heart Ventricles
Image Processing, Computer-Assisted
Materials Testing
Microscopy, Confocal

Source

Open in PubMed

Identifiers

PMID: 10701455
DOI: 10.1016/s0142-9612(99)00189-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microscopy, Electron, Scanning

Muscle Proteins

Myocardium

Phenotype