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Article

Global regulatory mutations in csrA and rpoS cause severe central carbon stress in Escherichia coli in the presence of acetate.

Journal of bacteriology - 1 Mar 2000

Wei B, Shin S, LaPorte D, Wolfe A J, Romeo T

Abstract excerpt

The csrA gene encodes a small RNA-binding protein, which acts as a global regulator in Escherichia coli and other bacteria (T. Romeo, Mol. Microbiol. 29:1321-1330, 1998). Its key regulatory role in central carbon metabolism, both as an activator of glycolysis and as a potent repressor of glycogen biosynthesis and gluconeogenesis, prompted us to examine the involvement of csrA in acetate metabolism and the...

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Identifiers

PMID: 10692369
DOI: 10.1128/JB.182.6.1632-1640.2000
PMCID: PMC94461

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Global regulatory mutations in csrA and rpoS cause severe central carbon stress in Escherichia coli in the presence of acetate.PMID 10692369Read ↗

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The Csr System Regulates Escherichia coli Fitness by Controlling Glycogen Accumulation and Energy Levels.Semantic proximity Read ↗

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