Article
Comparative transcriptome analysis between csrA-disruption Clostridium acetobutylicum and its parent strain.
Molecular bioSystems - 1 May 2015
Tan Yang, Liu Zi-Yong, Liu Zhen, Zheng Hua-Jun, Li Fu-Li
Abstract excerpt
The genome of Clostridium acetobutylicum contains the gene encoding CsrA, a carbon storage regulator. We investigated the function of CsrA in C. acetobutylicum by insertionally inactivating the encoding gene, CA_C2209 using the ClosTron. Disruption of csrA obviously decreases the growth of the organism and reduces the yield of acetone, butanol and ethanol (ABEs). Like the csrA in Escherichia coli, RNA-seq and...
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