Article
Variant transthyretin (TTR) amyloidosis in Argentina. Detection of the trait by electrospray ionization mass spectrometry of lyophilized TTR immunoprecipitate.
Scandinavian journal of clinical and laboratory investigation - 1 Dec 1999
Lendoire J C, Trigo P, Aziz H, Romero M C, Inventarza O, Ando Y, Tashima K, Ohlsson P I, Cederquist K, Holmgren G, Suhr O B
Abstract excerpt
We have developed a quick and reliable diagnostic method for detecting variant forms of transthyretin (TTR); namely, centrifugal concentration followed by electrospray ionization mass spectrometry (ESI-MS). Argentinian patients from three families with neuropathic amyloidosis and their relatives were screened for mutated TTR by ESI-MS. In order to facilitate transportation, we investigated the impact storage had...
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