Article
Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease.
The Journal of clinical endocrinology and metabolism - 1 Feb 2000
Vaidya B, Imrie H, Geatch D R, Perros P, Ball S G, Baylis P H, Carr D, Hurel S J, James R A, Kelly W F, Kemp E H, Young E T, Weetman A P, Kendall-Taylor P, Pearce S H
Abstract excerpt
Although autoimmune Addison's disease (AAD) may occur as a component of the monogenic autoimmune polyendocrinopathy type 1 syndrome (APS1), it is most commonly found as an isolated disorder or associated with the autoimmune polyendocrinopathy type 2 syndrome (APS2). It is likely that sporadic (non-APS1) AAD is inherited as a complex trait; however, apart from the major histocompatibility complex, the...
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