Genetic dissection of autoimmune polyendocrine syndrome type 2: common origin of a spectrum of phenotypes.

Abstract excerpt

Autoimmune diseases constitute a heterogeneous group of disorders characterized by the loss of immune tolerance to self-antigens. Despite their distinct clinical picture, there is growing evidence that common molecular mechanisms may contribute to the whole spectrum of autoimmune diseases. This theory is strongly supported by the existence of the autoimmune polyendocrine syndromes (APS). Thus, the clinical...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to AIRE gene
• Share to Genetic Predisposition to Disease
• Share to Phenotype