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Article

Conserved composition of mammalian box H/ACA and box C/D small nucleolar ribonucleoprotein particles and their interaction with the common factor Nopp140.

Molecular biology of the cell - 1 Feb 2000

Yang Y, Isaac C, Wang C, Dragon F, Pogacic V, Meier U T

Abstract excerpt

Small nucleolar ribonucleoprotein particles (snoRNPs) mainly catalyze the modification of rRNA. The two major classes of snoRNPs, box H/ACA and box C/D, function in the pseudouridylation and 2'-O-methylation, respectively, of specific nucleotides. The emerging view based on studies in yeast is that each class of snoRNPs is composed of a unique set of proteins. Here we present a characterization of mammalian...

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Identifiers

PMID: 10679015
DOI: 10.1091/mbc.11.2.567
PMCID: PMC14794

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