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Article

Role of Group A Streptococcal Virulence Factors in Adherence to Keratinocytes

1 Mar 2000

Abstract excerpt

To evaluate the role of putative group A streptococcal virulence factors in the initiation of skin infections, we compared the adherence of a wild-type M49-protein skin-associated strain to that of a series of 16 isogenic mutants created by insertional inactivation of virulence genes. None of the mutants, including the M-protein-deficient (emm mutant) strain, displayed reduced adherence to early-passage cultured...

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PMID: 10678929
DOI: 10.1128/iai.68.3.1215-1221.2000

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