Article
Factor V Leiden and allogeneic bone marrow transplantation: chimerism as a confounding factor in genetic test interpretation.
Clinical and laboratory haematology - 1 Dec 1999
Chiusolo P, Sica S, Salutari P, D'Onofrio G, Stefano V D, Ccirillo N P, Leone G
Abstract excerpt
Factor V Leiden is one of the most common genetic conditions predisposing to venous thrombosis. Diagnosis is currently made by plasma activity assay for activated protein C (APC) resistance or polymerase chain reaction (PCR)-based DNA assay. The occurrence of factor V Leiden is reported in a patient affected by acute myeloid leukaemia submitted to allogeneic bone marrow transplantation from an HLA identical...
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