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Article

False negative factor V Leiden assay following allogeneic stem cell transplant.

British journal of haematology - 1 Mar 1998

Crookston K P, Henderson R, Chandler W L

Abstract excerpt

We report a case where a phenotypic test (an activity assay for activated protein C resistance) correctly indicated that the patient had an abnormality, whereas the initial genetic test (a PCR-based DNA assay used to detect the mutation in the FV gene) incorrectly indicated that the patient did not. The apparent false negative result of the DNA-based test was due to the use of peripheral blood leucocytes for DNA...

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Identifiers

PMID: 9504649
DOI: 10.1046/j.1365-2141.1998.00585.x

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