Mutations in the gene encoding the alpha-subunit of the Gs protein in molar pregnancy.

doi:10.1385/ENDO:11:1:83

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Article

Mutations in the gene encoding the alpha-subunit of the Gs protein in molar pregnancy.

Endocrine - 1 Aug 1999

Garon G, LeHoux J G, Bessette P

Abstract excerpt

Molar pregnancy is a gestational trophoblastic disease associated with a trophoblastic proliferation and a protein synthesis alteration. It is characterized by the presence of hydatiform moles, which are fluid-filled cysts derived from the chorionic villi of the placenta. Recent studies have reported a reduced expression of several types of G proteins including Gsalpha in molar pregnancies suggesting alterations...

Topics

Adult
Alleles
Base Sequence
Exons
Female
GTP-Binding Protein alpha Subunits, Gs
Humans
Hydatidiform Mole
Introns
Molecular Sequence Data
Mutation
Oncogene Proteins
Polymorphism, Genetic
Pregnancy
Reverse Transcriptase Polymerase Chain Reaction

Source

Open in PubMed

Identifiers

PMID: 10668646
DOI: 10.1385/ENDO:11:1:83

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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