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Article

Mutations in the gene encoding the alpha-subunit of the Gs protein in molar pregnancy.

Endocrine - 1 Aug 1999

Garon G, LeHoux J G, Bessette P

Abstract excerpt

Molar pregnancy is a gestational trophoblastic disease associated with a trophoblastic proliferation and a protein synthesis alteration. It is characterized by the presence of hydatiform moles, which are fluid-filled cysts derived from the chorionic villi of the placenta. Recent studies have reported a reduced expression of several types of G proteins including Gsalpha in molar pregnancies suggesting alterations...

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Identifiers

PMID: 10668646
DOI: 10.1385/ENDO:11:1:83

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Mutations in the gene encoding the alpha-subunit of the Gs protein in molar pregnancy.PMID 10668646Read ↗

Gestational Trophoblastic DiseaseSemantic proximity Read ↗

The risk of post-molar gestational trophoblastic neoplasia is higher in heterozygous than in homozygous complete hydatidiform molesSemantic proximity Read ↗

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A familial case of recurrent hydatidiform molar pregnancies with biparental genomic contribution.Semantic proximity Read ↗

Serum proteins in vesicular fluid of hydatidiform moles: a lack of selectivity of molar trophoblast in the transfer of maternal serum proteins.Semantic proximity Read ↗

Inactivating and activating mutations of the Gs alpha gene.Semantic proximity Read ↗

Genetic differentiation of complete hydatidiform moles coexisting with normal fetuses by short tandem repeat-derived deoxyribonucleic acid polymorphism analysis.Semantic proximity Read ↗

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