Article
A familial case of recurrent hydatidiform molar pregnancies with biparental genomic contribution.
Human genetics - 1 Jan 2000
Helwani M N, Seoud M, Zahed L, Zaatari G, Khalil A, Slim R
Abstract excerpt
Hydatidiform mole is a benign trophoblastic neoplasia characterized by an abnormal development of the embryo and proliferation of placental villi. Using microsatellite markers amplified by the polymerase chain reaction, we have performed a genetic study on eight independent molar tissues occurring in two sisters. Karyotype and genotype data demonstrate a diploid and biparental constitution in seven of the...
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