Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The polymorphisms of codon 727 and 52 of thyroid-stimulating hormone receptor gene are not associated with mitral valve prolapse syndrome in Taiwan Chinese.

Japanese heart journal - 1 Nov 2002

Chou Hsiang-Tai, Shi Yi-Ru, Chang Chwen-Tzuei, Tsai Fuu-Jen

Abstract excerpt

A germline mutation of the thyroid-stimulating hormone receptor (TSHR) gene has been reported to be associated with thyrotoxicosis and mitral valve prolapse syndrome (MVPS) in a Chinese family. The role of TSHR genetic variants in MVPS has not been well studied. This study investigated the possible relationship between the polymorphisms of codon 727 and 52 of the TSHR gene and MVPS among the Chinese population in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Mitral Valve Prolapse

Share to Polymorphism, Genetic

Share to Receptors, Thyrotropin

Share to Restriction Mapping

Share to Taiwan

Source

Identifiers

PMID: 12558129
DOI: 10.1536/jhj.43.655

Genes

TSHR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

The polymorphisms of codon 727 and 52 of thyroid-stimulating hormone receptor gene are not associated with mitral valve prolapse syndrome in Taiwan Chinese.PMID 12558129Read ↗

No association between a thyrotropin receptor gene polymorphism and Graves' disease in the female population.Semantic proximity Read ↗

A germline single nucleotide polymorphism at the intracellular domain of the human thyrotropin receptor does not have a major effect on the development of Graves' disease.Semantic proximity Read ↗

A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family.Semantic proximity Read ↗

Analysis of the genetic variability of the 1st (CCC/ACC, P52T) and the 10th exons (bp 1012-1704) of the TSH receptor gene in Graves' disease.Semantic proximity Read ↗

[Polymorphism of the 52 triplet gene (nucleotide 253) of the TSH receptor in Basedow-Graves patients and in healthy controls].Semantic proximity Read ↗

Lack of association between a polymorphism of human thyrotropin receptor gene and autoimmune thyroid disease.Semantic proximity Read ↗

Analysis of mutations in exon 1 of the human thyrotropin receptor gene: high frequency of the D36H and P52T polymorphic variants.Semantic proximity Read ↗

Lack of association between a polymorphism in the coding region of the thyrotropin receptor gene and Graves' disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.