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Article

High-resolution micro-computed tomography analyses of the abnormal trabecular bone structures in klotho gene mutant mice.

The Journal of endocrinology - 1 Feb 2000

Yamashita T, Nabeshima Y, Noda M

Abstract excerpt

Inactivation mutation of the recently discovered klotho gene in mice causes a syndrome resembling aging. Manifestations include short life span, atherosclerosis, gonadal atropy, skin atropy, emphysema, ataxia and ectopic calcification. These mice also exhibit abnormally high bone density in the e...

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Identifiers

PMID: 10657859
DOI: 10.1677/joe.0.1640239

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10657859-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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