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Article

Sry induces cell proliferation in the mouse gonad.

Development (Cambridge, England) - 1 Jan 2000

Schmahl J, Eicher E M, Washburn L L, Capel B

Abstract excerpt

Sry is the only gene on the Y chromosome that is required for testis formation in mammals. One of the earliest morphological changes that occurs as a result of Sry expression is a size increase of the rudimentary XY gonad relative to the XX gonad. Using 5'-bromo-2'-deoxyuridine (BrdU) incorporation to label dividing cells, we found that the size increase corresponds with a dramatic increase in somatic cell...

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Identifiers

PMID: 10654601
DOI: 10.1242/dev.127.1.65

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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