Article
Adaptation to the environment: Streptococcus pneumoniae, a paradigm for recombination-mediated genetic plasticity?
Molecular microbiology - 1 Jan 2000
Claverys J P, Prudhomme M, Mortier-Barrière I, Martin B
Abstract excerpt
Genetic plasticity plays a central role in the biology of the human pathogen Streptococcus pneumoniae. This is illustrated by the existence of at least 90 different capsular types (the polysaccharide capsule has an essential antiphagocytic function) as well as by the rapid emergence of penicillin-resistant (PenR) pneumococcal isolates. Natural genetic transformation is believed to be essential for this genetic...
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