Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage.

Stroke - 1 Jun 2012

Brouwers H Bart, Biffi Alessandro, Ayres Alison M, Schwab Kristin, Cortellini Lynelle, Romero Javier M, Rost Natalia S, Viswanathan Anand, Greenberg Steven M, Rosand Jonathan, Goldstein Joshua N

Abstract excerpt

BACKGROUND AND PURPOSE: Hematoma volume is the most potent predictor of outcome in spontaneous intracerebral hemorrhage (ICH), and hematoma expansion after hospital presentation occurs in up to 40% of individuals. Among patients with lobar ICH, the apolipoprotein E (APOE) ε2 allele predicts larger hematoma volumes at presentation. We investigated whether the ε2 allele also identifies individuals at increased risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Apolipoproteins E

Share to Cerebral Hemorrhage

Share to APOE gene

Share to Genetic Predisposition to Disease

Share to Genotype

Source

Open in PubMed Open full text

Identifiers

PMID: 22535266
DOI: 10.1161/STROKEAHA.111.643262
PMCID: PMC3361564

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Apolipoprotein E genotype predicts hematoma expansion in lobar intracerebral hemorrhage.PMID 22535266Read ↗

Apolipoprotein E genotype predicts subarachnoid extension in spontaneous intracerebral haemorrhage.Semantic proximity Read ↗

APOE genotype and extent of bleeding and outcome in lobar intracerebral haemorrhage: a genetic association study.Semantic proximity Read ↗

Factors associated with intracerebral hemorrhage in confirmed cerebral amyloid angiopathy.Semantic proximity Read ↗

Variants at APOE influence risk of deep and lobar intracerebral hemorrhage.Semantic proximity Read ↗

Apolipoprotein E genotype is associated with CT angiography spot sign in lobar intracerebral hemorrhage.Semantic proximity Read ↗

Association between apolipoprotein E gene polymorphism and early MR findings in individuals with acute intracerebral hemorrhage: A retrospective cohort analysis.Semantic proximity Read ↗

U-shaped Association of Admission Fibrinogen Levels with Perihematomal Edema in Hypertensive Intracerebral HemorrhageSemantic proximity Read ↗

Racial/ethnic variation of APOE alleles for lobar intracerebral hemorrhage.Semantic proximity Read ↗

Association of APOE genotype with CT markers of cerebral amyloid angiopathy in spontaneous intracerebral haemorrhage.Semantic proximity Read ↗

Apolipoprotein E modifies neurological outcome by affecting cerebral edema but not hematoma size after intracerebral hemorrhage in humans.Semantic proximity Read ↗

von Willebrand factor genetic variant associated with hematoma expansion after intracerebral hemorrhage.Semantic proximity Read ↗

Incidence of Convexal Subarachnoid Hemorrhage in the Elderly: The Mayo Clinic Study of Aging.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.