Article
Changes in a murine leukemia virus (MLV) receptor encoded by an alphavirus vector during passage in cells expressing the MLV envelope.
Virology - 1 Feb 2000
Kazachkov Y, Long D, Wang C, Silver J
Abstract excerpt
We constructed alphavirus vectors encoding the ecotropic murine leukemia virus (MLV) receptor mCAT1. Cells electroporated with these vector RNAs expressed mCAT1 protein and fused with cells that expressed a fusogenic form of the MLV envelope on the cell surface. Electroporated cells also released submicron particles that were infectious in envelope-expressing cells. Infection resulted in giant syncytia that could...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
