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Article

Dopamine receptor D4 is not associated with antidepressant activity of sleep deprivation.

Psychiatry research - 20 Dec 1999

Serretti A, Benedetti F, Colombo C, Lilli R, Lorenzi C, Smeraldi E

Abstract excerpt

Total sleep deprivation (TSD) is an effective treatment for mood disorders which is thought to act through an enhancement in several neurotransmitter pathways including dopaminergic transmission. However, not all patients respond to TSD and genetic factors are likely to play a major role in determining TSD response. The aim of this study is to investigate the influence of dopamine receptor D4 exon 3 (DRD4)...

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Source

Identifiers

PMID: 10646829
DOI: 10.1016/s0165-1781(99)00096-7

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Dopamine receptor D4 is not associated with antidepressant activity of sleep deprivation.PMID 10646829Read ↗

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