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Article

Loss of Osteocyte Integrity in Association with Microdamage and Bone Remodeling After Fatigue In Vivo

1 Jan 2000

Abstract excerpt

As a result of fatigue, bone sustains microdamage, which is then repaired by bone-remodeling processes. How osteoclastic activity is targeted at the removal of microdamaged regions of bone matrix is unknown. In the current studies, we tested the hypothesis that changes in osteocyte integrity, through the initiation of regulated cell death (apoptosis), are associated with fatigue-related microdamage and bone...

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PMID: 10646115
DOI: 10.1359/jbmr.2000.15.1.60

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