Article
Differential expression of neural cell adhesion molecule isoforms in normal and glaucomatous human optic nerve heads.
Brain research. Molecular brain research - 10 Dec 1999
Ricard C S, Pena J D, Hernandez M R
Abstract excerpt
Type 1B astrocytes of the human optic nerve head (ONH) constitutively express neural cell adhesion molecule (NCAM) in vivo and in vitro. Increased synthesis of NCAM has been detected in reactive astrocytes in the glaucomatous ONH of human donor eyes. Several NCAM isoforms are generated through alternate RNA splicing in tissue- and disease-specific patterns. In this study, we analyzed expression of NCAM isoforms...
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