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Article

The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles.

Infection and immunity - 1 Feb 2000

Centurion-Lara A, Godornes C, Castro C, Van Voorhis W C, Lukehart S A

Abstract excerpt

We have previously shown that the TprK antigen of T. pallidum, Nichols strain, is predominantly expressed in treponemes obtained 10 days after infection and that the hydrophilic domain of TprK is a target of opsonic antibodies and confers significant protection against homologous challenge. The T. pallidum genome sequence reported the presence of a single copy of the tprK gene in the Nichols strain. In the...

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Identifiers

PMID: 10639452
DOI: 10.1128/IAI.68.2.824-831.2000
PMCID: PMC97211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The tprK gene is heterogeneous among Treponema pallidum strains and has multiple alleles.PMID 10639452Read ↗

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