Article
Candida albicans mutants deficient in respiration are resistant to the small cationic salivary antimicrobial peptide histatin 5.
Antimicrobial agents and chemotherapy - 1 Feb 2000
Gyurko C, Lendenmann U, Troxler R F, Oppenheim F G
Abstract excerpt
Histatins are a group of small cationic peptides in human saliva which are well known for their antibacterial and antifungal activities. In a previous study we demonstrated that histatin 5 kills both blastoconidia and germ tubes of Candida albicans in a time- and concentration-dependent manner at 37 degrees C, whereas no killing was detected at 4 degrees C. This indicated that killing activity depends on cellular...
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