Article

The role of metal binding in the function of the human salivary antimicrobial peptide histatin-5

2022-01-07

Abstract excerpt

<h4>ABSTRACT</h4> Antimicrobial peptides (AMPs) are key components of diverse host innate immune systems. The family of human salivary AMPs known as histatins bind Zn and Cu. Fluctuations in Zn and Cu availability play significant roles in the host innate immune response (so-called “nutritional immunity”). Thus, we hypothesised that histatins contribute to nutritional immunity by influencing host Zn and/or Cu ava...

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Literature Corpus work: 71b3b934-f9a6-535b-b368-019073f40d53
DOI: 10.1101/2022.01.07.472205

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