Article
Aberrant overexpression of 53BP2 mRNA in lung cancer cell lines
14 Jan 2000
Abstract excerpt
The p53-binding protein 2 (53BP2) was identified as a binding protein to a tumor suppressor p53. We examined the genetic aberrations of 53BP2 gene in various human cancer cell lines. Although no gross genomic alteration or mutation of 53BP2 gene was observed, 53BP2 mRNA levels were highly variable. There was no association between the 53BP2 mRNA level and the p53 status. When we examined sensitivities of these...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.