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Article

Histone Acetylation and Reactivation of Epstein-Barr Virus from Latency

15 Jan 2000

Abstract excerpt

Induction of the viral BZLF1 gene has previously been shown to be one of the first steps in the reactivation of Epstein-Barr virus (EBV). Using an EBV oriP episomal vector system, we have reconstituted the regulation of the promoter for BZLF1 on stably transfected episomes, mapped promoter elements required for that regulation, and investigated mechanisms that may control the switch between latency and the lytic...

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Identifiers

PMID: 10623733
DOI: 10.1128/jvi.74.2.710-720.2000

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