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Expression, purification and charaterization of recombinant mouse MT5‐MMP protein products

30 Nov 1999

Abstract excerpt

We have recently identified the fifth member of the membrane-type matrix metalloproteinase subfamily, MT5-MMP/MMP24, which is expressed in a brain specific manner (Duanqing Pei (1999) J. Biol. Chem. 274, 8925-8932). To further characterize its enzymic properties, an expression construct was engineered to produce MT5-MMP as a soluble and active form by truncating its transmembrane domain. Stable expression cell...

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PMID: 10622708
DOI: 10.1016/s0014-5793(99)01534-3

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