Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.

The Journal of biological chemistry - 26 Mar 1999

Pei D

Abstract excerpt

A new member of the membrane-type matrix metalloproteinase (MT-MMP) subfamily tentatively named MT5-MMP was isolated from mouse brain cDNA library. It is predicted to contain (i) a candidate signal sequence, (ii) a propeptide region with the highly conserved PRCGVPD sequence, (iii) a potential furin recognition motif RRRRNKR, (iv) a zinc-binding catalytic domain, (v) a hemopexin-like domain, (vi) a 24-residue...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Embryonic and Fetal Development
Share to Enzyme Activation
Share to Enzyme Precursors

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gelatinases

Share to Gene Expression Regulation, Developmental

Share to Gene Expression Regulation, Enzymologic

Share to Metalloendopeptidases

Share to Sequence Homology, Amino Acid

Source

Identifiers

PMID: 10085137
DOI: 10.1074/jbc.274.13.8925

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.PMID 10085137Read ↗

Membrane-Type 5 Matrix Metalloproteinase (MT5-MMP): Background and Proposed Roles in Normal Physiology and DiseaseSemantic proximity Read ↗

Expression, purification and charaterization of recombinant mouse MT5‐MMP protein productsSemantic proximity Read ↗

Mouse Chromosome 17A3.3 Contains 13 Genes That Encode Functional Tryptic-like Serine Proteases with Distinct Tissue and Cell Expression PatternsSemantic proximity Read ↗

Update of human and mouse matrix metalloproteinase familiesSemantic proximity Read ↗

MT4-MMP: The GPI-Anchored Membrane-Type Matrix Metalloprotease with Multiple Functions in DiseasesSemantic proximity Read ↗

Matrix metalloproteinase-21, the human orthologue for XMMP, is expressed during fetal development and in cancerSemantic proximity Read ↗

Identification and characterization of novel mouse and human ADAM33s with potential metalloprotease activitySemantic proximity Read ↗

MT4-(MMP17) and MT6-MMP (MMP25), A unique set of membrane-anchored matrix metalloproteinases: properties and expression in cancerSemantic proximity Read ↗

ADAM-TS5, ADAM-TS6, and ADAM-TS7, Novel Members of a New Family of Zinc MetalloproteasesSemantic proximity Read ↗

Genome-wide identification of Xenopus matrix metalloproteinases: conservation and unique duplications in amphibiansSemantic proximity Read ↗

Identification and Characterization of ADAMTS-20 Defines a Novel Subfamily of Metalloproteinases-Disintegrins with Multiple Thrombospondin-1 Repeats and a Unique GON DomainSemantic proximity Read ↗

The Matrix Metalloproteinase-14 (MMP-14) Gene Is Structurally Distinct from Other MMP Genes and Is Co-expressed with the TIMP-2 Gene during Mouse EmbryogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.