Article
Substrate specificity of lignin peroxidase and a S168W variant of manganese peroxidase.
Archives of biochemistry and biophysics - 1 Jan 2000
Timofeevski S L, Nie G, Reading N S, Aust S D
Abstract excerpt
Lignin peroxidase (LiP) and manganese peroxidase (MnP) are structurally similar heme-containing enzymes secreted by white-rot fungi. Unlike MnP, which is only specific for Mn(2+), LiP has broad substrate specificity, but it is not known if this versatility is due to multiple substrate-binding sites. We report here that a S168W variant of MnP from Phanerochaete chrysosporium not only retained full Mn(2+) oxidase...
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