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Article

Using an artificial tryptophan "wire" in cytochrome c peroxidase for oxidation of organic substrates.

Dalton transactions (Cambridge, England : 2003) - 22 Aug 2017

Field Mackenzie J, Bains Rajneesh K, Warren Jeffrey J

Abstract excerpt

Lignolytic peroxidases use an electron transfer (ET) pathway that involves amino acid-mediated substrate oxidation at the surface of the protein rather than at an embedded heme site. In many of these peroxidases, redox catalysis takes place at a substrate accessible tyrosine or tryptophan (Trp) amino acid. Here, we describe new mutants of cytochrome c peroxidase (CcP) that were designed to incorporate a Trp-based...

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PMID: 28792039
DOI: 10.1039/c7dt02330h

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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