Article
Effect of genotype on the angiotensin-converting enzyme mRNA level in human atria.
Clinical and experimental pharmacology & physiology - 1 May 1997
Tamaki S, Iwai N, Ohmichi N, Shimoike H, Izumi M, Nakamura Y, Kinoshita M, Katsuyama K, Sugita T, Watarida S, Mori A
Abstract excerpt
1. To clarify the mechanism of the association between I/D polymorphism of the angiotensin-converting enzyme (ACE) gene and various cardiovascular disease, ACE mRNA levels in human atrial appendages were assessed in relation to the genotype of the ACE gene. 2. Angiotensin-converting enzyme mRNA levels were positively correlated with age and tended to show a positive correlation with mean pulmonary pressure (mPA)....
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