Article
Luteinizing hormone induction of ovarian tumors: oligogenic differences between mouse strains dictates tumor disposition.
Proceedings of the National Academy of Sciences of the United States of America - 4 Jan 2000
Keri R A, Lozada K L, Abdul-Karim F W, Nadeau J H, Nilson J H
Abstract excerpt
The use of fertility drugs has continued to grow since their introduction in the 1960s. Accompanying this increase has been the speculation that repetitive use of these drugs can cause ovarian tumors or cancer. We recently reported that transgenic mice with chronically elevated luteinizing hormone (LH), an analog of which is commonly used in fertility regimens, develop granulosa cell (GC) tumors. In this report...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.