Fluctuation analysis on mutation models with birth-date dependence.

Abstract excerpt

The classic Luria-Delbrück model can be interpreted as a Poisson compound (number of mutations) of exponential mixtures (developing time of mutant clones) of geometric distributions (size of a clone in a given time). This "three-ingredients" approach is generalized in this paper to the case where the split instant distributions of cells are not i.i.d. : the lifetime of each cell is assumed to depend on its birth...

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