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Article

A celR mutation affecting transcription of cellulase genes in Thermobifida fusca.

Journal of bacteriology - 1 Jan 2000

Spiridonov N A, Wilson D B

Abstract excerpt

Biosynthesis of extracellular cellulases in the cellulose-degrading actinomycete Thermobifida fusca is controlled by a transcriptional regulator, CelR, and cellobiose, which acts as an inducer interfering with the CelR-DNA interaction. We report the identification and characterization of a mutation in the celR gene that changes Ala(55) in the hinge helix of CelR to Thr. The wild-type and mutant celR genes were...

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Identifiers

PMID: 10613893
DOI: 10.1128/JB.182.1.252-255.2000
PMCID: PMC94270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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