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Article

A global transcriptional regulator in Thermococcus kodakaraensis controls the expression levels of both glycolytic and gluconeogenic enzyme-encoding genes.

The Journal of biological chemistry - 16 Nov 2007

Kanai Tamotsu, Akerboom Jasper, Takedomi Shogo, van de Werken Harmen J G, Blombach Fabian, van der Oost John, Murakami Taira, Atomi Haruyuki, Imanaka Tadayuki

Abstract excerpt

We identified a novel regulator, Thermococcales glycolytic regulator (Tgr), functioning as both an activator and a repressor of transcription in the hyperthermophilic archaeon Thermococcus kodakaraensis KOD1. Tgr (TK1769) displays similarity (28% identical) to Pyrococcus furiosus TrmB (PF1743), a...

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PMID: 17875647
DOI: 10.1074/jbc.M703424200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17875647-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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